NICOTINAMIDE MONONUCLEOTIDE (NMN) IS ATTRACTING ATTENTION AS AN INGREDIENT WITH ANTI-AGING PROPERTIES. HOWEVER, THERE ARE STILL MANY ASPECTS OF ITS EFFECTS AND MECHANISMS THAT REMAIN UNCLEAR, AND NUMEROUS TRIALS ARE CURRENTLY UNDERWAY AROUND THE WORLD.
OF COURSE, RESEARCH ON THE COSMETIC EFFECTS OF NMN IS NO EXCEPTION. THIS ARTICLE DESCRIBES THE EFFECTS OF NMN ON BEAUTY THAT ARE BECOMING CLEAR, AS WELL AS HOW TO CONSUME IT AND WHAT TO LOOK OUT FOR WHEN EXPECTING COSMETIC EFFECTS.
HOW NMN HAS AN EFFECT ON BEAUTY
ESSENTIAL TO THE ANTI-AGING EFFECT OF NMN IS A COMPONENT CALLED NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE), WHICH IS PRODUCED FROM NMN.
NAD+ IS ESSENTIAL FOR CELLULAR ENERGY PRODUCTION AND IS ALSO INVOLVED IN THE ACTIVATION OF THE SIRTUIN GENE (ALSO KNOWN AS THE LONGEVITY GENE), WHICH CONTROLS CHANGES ASSOCIATED WITH AGING. IN OTHER WORDS, NMN TAKEN INTO THE BODY IS RAPIDLY CONVERTED TO NAD+, WHICH IS THOUGHT TO IMPROVE BODILY FUNCTIONS AND EXHIBIT ANTI-AGING EFFECTS.
SO WHAT ARE THE EFFECTS OF NMN ON BEAUTY, ESPECIALLY ON THE SKIN?
ACCORDING TO RESEARCH CONDUCTED IN JAPAN AND OVERSEAS USING HUMAN SKIN CULTURE MODELS, NMN IS EXPECTED TO HAVE VARIOUS EFFECTS SUCH AS IMPROVING SKIN PROBLEMS AND ACTIVATING METABOLISM.
Improvement of skin problems by using lotion (serum)
TESTS USING HUMAN SKIN CULTURE MODELS HAVE CONFIRMED THE FOLLOWING EFFECTS WHEN NMN IS GIVEN TO THE SKIN
ANTI-AGING EFFECT OF NMN ON SKIN
WHEN A 5% AQUEOUS SOLUTION OF NMN WAS ADDED TO THE STRATUM CORNEUM SIDE OF A HUMAN SKIN CULTURE MODEL, THE AMOUNT OF NMN IN THE CELLS INCREASED APPROXIMATELY 100-FOLD AND THE AMOUNT OF NAD+ INCREASED APPROXIMATELY 4-FOLD AFTER 24 HOURS. THE RESULTS ALSO SHOWED THAT THE ADDITION OF NMN INDUCED THE EXPRESSION OF ENZYMES INVOLVED IN THE SYNTHESIS OF NATURAL MOISTURIZING COMPONENTS.
THESE FINDINGS SUGGEST THAT THE APPLICATION OF NMN TO THE EPIDERMIS TO ACTIVATE SIRTUINS MAY STIMULATE THE PRODUCTION OF NATURAL MOISTURIZERS AND REDUCE SKIN AGING.
EFFECT OF NMN ON SKIN PIGMENTATION
WHEN NMN WAS APPLIED TO YOUNG AND AGED MELANOCYTES, THERE WAS NO PARTICULAR CHANGE IN YOUNG MELANOCYTES, BUT A MARKED DECREASE IN MELANIN PRODUCTION IN AGED MELANOCYTES. NMN ALSO EFFICIENTLY REDUCED MELANIN PRODUCTION IN A HUMAN SKIN CULTURE MODEL CONTAINING AGED MELANOCYTES. THIS INHIBITORY EFFECT ON MELANIN PRODUCTION WAS ALSO REPORTED AND PROVEN TO OCCUR AT THE RNA LEVEL.
THESE RESULTS SUGGEST THAT NMN MAY HELP IMPROVE AGE-RELATED SKIN PIGMENTATION.
THUS, THE EFFECTS OF NMN APPLIED DIRECTLY TO THE SKIN HAVE BEEN REPORTED ONE AFTER ANOTHER. IF YOU ARE CONCERNED ABOUT SKIN AGING OR BLEMISHES, YOU MAY CONSIDER INCORPORATING NMN AS A LOTION OR SERUM CONTAINING NMN.
Supplementation improves metabolism
WHAT KIND OF COSMETIC EFFECTS CAN BE EXPECTED WHEN NMN IS TAKEN INTO THE BODY AS A SUPPLEMENT?
WHEN NMN IS TAKEN BY MOUTH, IT IS RAPIDLY CONVERTED TO NAD+ IN THE BODY AND IS THOUGHT TO EXERT VARIOUS ANTI-AGING EFFECTS. ONE OF THESE IS THE IMPROVEMENT OF METABOLISM.
Improved metabolism is an essential element for maintaining youthful and beautiful skin.
If metabolism improves and the skin's turnover cycle is better organized, skin problems such as rough skin, clogged pores, and acne will be less likely to occur. In addition, with a smooth turnover, the skin will become beautiful and healthy, and its texture will become more even, which will improve its elasticity and luster.
Note that the effects obtained from supplements and lotion (serum) are different.
It is important to note that supplements and lotions or serums have different effects that can be obtained.
ALTHOUGH LOTIONS AND SERUMS PENETRATE THE SKIN, THEY ARE NOT TAKEN INTO THE BODY AS MUCH AS ORALLY. THEREFORE, UNLESS USED IN EXCESS, THE EFFECTS OF LOTIONS AND SERUMS CONTAINING NMN APPLIED TO THE SKIN MAY BE LIMITED TO AN INCREASE IN THE AMOUNT OF NMN AND NAD+ IN SKIN CELLS, LOCALIZED ACTIVATION OF SIRTUINS, AND SUPPRESSION OF MELANIN PRODUCTION.
ON THE OTHER HAND, WHEN NMN IS INGESTED THROUGH SUPPLEMENTS OR FOODS, ITS ANTI-AGING EFFECTS ARE NOT LIMITED TO THE SKIN. NMN TAKEN INTO THE BODY IS CONVERTED TO NAD+, WHICH SUPPORTS ENERGY PRODUCTION AND FUNCTIONAL IMPROVEMENT OF CELLS AND TISSUES, AND AS A RESULT, VARIOUS COSMETIC EFFECTS MAY BE EXPECTED.
HOW CAN NMN BE INCORPORATED?
CONTINUOUS AND EASY WAYS TO INCORPORATE NMN INCLUDE APPLICATION OF LOTIONS AND SERUMS, AND INTAKE THROUGH DIET AND SUPPLEMENTS.
SO WHAT IS THE BEST WAY TO INCORPORATE NMN FOR COSMETIC PURPOSES? LET'S COMPARE EACH METHOD.
The easiest way is cosmetics (serum)
IF EASE IS A PRIORITY, WE RECOMMEND THE USE OF LOTIONS AND SERUMS CONTAINING NMN.
OF COURSE, NMN IS NOT TAKEN UP MUCH BY THE BODY WHEN LOTIONS AND SERUMS ARE APPLIED TO THE SKIN. ALTHOUGH THE EFFECT IS LIMITED, APPLICATION OF NMN CAN BE EXPECTED TO INCREASE THE AMOUNT OF NAD+ IN SKIN CELLS, WHICH MAY LEAD TO SUPPRESSION OF SKIN PROBLEMS. IT IS ALSO RECOMMENDED FOR THOSE WHO WISH TO IMPROVE AGE SPOTS AND WRINKLES OR RESTORE SKIN ELASTICITY AND LUSTER.
ALTHOUGH THERE ARE MANY NMN-CONTAINING COSMETICS ON THE MARKET, THE PURITY AND AMOUNT OF NMN CONTAINED IN EACH PRODUCT DIFFER. WHEN PURCHASING A PRODUCT, BE SURE TO SELECT A PRODUCT FROM A RELIABLE MANUFACTURER BY CHECKING THE PURITY AND AMOUNT OF INGREDIENTS, THE CONTENT OF INGREDIENTS INCLUDING ADDITIVES, AND WHETHER OR NOT IT HAS BEEN CHECKED BY A THIRD-PARTY ORGANIZATION.
Can also be obtained from food
NMN CAN ALSO BE OBTAINED FROM FOODS; VEGETABLES RICH IN NMN INCLUDE EDAMAME, BROCCOLI, CUCUMBERS, AND CABBAGE.
However, the amount of NMN contained in these foods is negligible. Even edamame, which is said to contain a large amount of NMN, requires 21 kg (about 33,000 grains) to consume 100 mg of NMN. Furthermore, NMN is heat sensitive, and heating should be avoided when taking it from vegetables.
THEREFORE, FROM AN EFFICIENCY STANDPOINT, IT IS NOT RECOMMENDED TO TRY TO OBTAIN SUFFICIENT NMN LEVELS THROUGH DAILY DIET ALONE.
https://corp.abeyoando.co.jp/journal/nmn-food
TO EFFICIENTLY INCORPORATE NMN INTO YOUR BODY, YOU MAY WANT TO CONSIDER USING SUPPLEMENTS. SUPPLEMENTS ARE ALSO AVAILABLE FROM VARIOUS MANUFACTURERS. WE RECOMMEND PURCHASING SUPPLEMENTS FROM MANUFACTURERS THAT PROVIDE OBJECTIVE PROOF OF PURITY AND CONTENT.
WHAT TO EXPECT FROM THE COSMETIC EFFECTS OF NMN
LET'S NOW LOOK AT WHAT TO LOOK FOR WHEN TAKING NMN FOR COSMETIC PURPOSES.
NMN IS A NUTRIENT WITH POTENTIAL ANTI-AGING EFFECTS
NMN HAS BEEN REPORTED TO HAVE A NUMBER OF EFFECTS ON THE SKIN, AND ITS COSMETIC EFFECTS ARE THOUGHT TO BE ASSOCIATED WITH ITS ANTI-AGING PROPERTIES.
INHIBITION OF MELANIN PRODUCTION BY NMN HAS ALSO BEEN REPORTED, BUT THIS EFFECT WAS PARTICULARLY OBSERVED IN AGED MELANOCYTES.
THEREFORE, NMN IS CONSIDERED TO BE A NUTRIENT THAT PROVIDES COSMETIC BENEFITS ALONG WITH ANTI-AGING EFFECTS.
Effectiveness may vary from generation to generation
IN STUDIES ON MICE AND OTHER ANIMALS, NO SIGNIFICANT CHANGES WERE OBSERVED WHEN NMN WAS ADMINISTERED TO THE HEALTHY YOUNG GENERATION. ON THE OTHER HAND, IN THE MIDDLE-AGED AND ELDERLY GROUP, DIFFERENCES WERE OBSERVED BETWEEN THE NMN-TREATED AND NON-NMN-TREATED GROUPS.
IN HUMANS, THE AMOUNT OF BOTH NMN AND NAD+ IN THE BODY DECREASES WITH AGE, AND IN MIDDLE-AGED AND OLDER PEOPLE, IT IS SAID TO BE REDUCED TO ABOUT HALF OF WHAT IT WAS WHEN THEY WERE YOUNGER. THEREFORE, IT IS THOUGHT THAT IF THOSE WHO ARE BEGINNING TO EXPERIENCE AGE-RELATED CHANGES TAKE IN NMN, THEY WILL EXPERIENCE HIGHER ANTI-AGING AND COSMETIC EFFECTS THAN THOSE OF YOUNGER GENERATIONS.
NEVERTHELESS, THE AMOUNT OF NMN IN THE BODY VARIES FROM PERSON TO PERSON. WE RECOMMEND THAT EVEN YOUNGER GENERATIONS TAKE IN NMN AS A PREVENTIVE MEASURE IF THEY FEEL AGE-RELATED CHANGES, ETC.
summary
NMN IS QUICKLY CONVERTED TO NAD+ IN THE BODY AND EXERTS VARIOUS EFFECTS, INCLUDING AN ANTI-AGING EFFECT. ACCORDING TO RECENT RESEARCH REPORTS, NMN IS ALSO EXPECTED TO HAVE COSMETIC EFFECTS ASSOCIATED WITH IMPROVEMENT OF SKIN PROBLEMS AND METABOLISM.
HOWEVER, THE EFFECTS OBTAINED WILL VARY DEPENDING ON THE METHOD OF NMN INTAKE. IF YOU WANT TO OBTAIN BEAUTY EFFECTS BY WORKING DIRECTLY ON SKIN CELLS, YOU SHOULD CHOOSE A LOTION OR SERUM CONTAINING NMN. ON THE OTHER HAND, IF YOU WANT TO REGAIN YOUTHFULNESS FROM THE INSIDE OF YOUR BODY AND OBTAIN BEAUTY EFFECTS AS A RESULT, WE RECOMMEND THAT YOU TAKE NMN FROM FOOD SUCH AS SUPPLEMENTS.
IT IS BELIEVED THAT THE EFFECTS OF NMN ARE MORE EASILY FELT BY THOSE WHO ARE IN THE AGE GROUP THAT BEGINS TO NOTICE AGE-RELATED CHANGES. YOU MAY WANT TO CONSIDER TAKING NMN TO LIVE A MORE BEAUTIFUL LIFE IN THE FUTURE.