1. CHECK THE SAFETY OF NMN.
NMN IS ORIGINALLY PRODUCED IN THE HUMAN BODY, BUT ITS PRODUCTION DECREASES WITH AGE.
Therefore, supplementation is recommended, but because it is taken as a health food, its safety as a product must be maintained.
FOR EXAMPLE, A PRODUCT MANUFACTURED IN A FACTORY THAT MEETS GMP (GOOD MANUFACTURING PRACTICES) STANDARDS CAN BE SAID TO BE SAFE BECAUSE IT COMES FROM A GMP-CERTIFIED FACTORY, BUT THIS ALONE ONLY MEANS THAT THE PRODUCT HAS MET THE MANUFACTURING STANDARDS.
OTHER THINGS TO CHECK INCLUDE THAT THE MANUFACTURING PLANT IS ISO CERTIFIED FOR FOOD SAFETY MANAGEMENT "ISO" PROVIDED BY THE JAPAN QUALITY ASSURANCE ORGANIZATION.
GMP IS SPECIFIC TO PRODUCT QUALITY AND SAFETY, WHEREAS ISO PROVIDES BROADER STANDARDS FOR THE QUALITY OF MANAGEMENT SYSTEMS AND PROCESSES THROUGHOUT AN ORGANIZATION.
In the production of supplements, those produced in factories that have received both certifications are more reliable.
Because major mail-order websites make it easy for even less specialized manufacturers to sell supplements, special attention should be paid to safety.
In addition, there are two types of NMN, α-NMN and β-NMN, and NMN produced in the body is β-NMN, so be sure to choose this one.
2. Is the distributor of the supplement trustworthy?
Since online shopping is so easy these days with smartphones, very many people make purchase decisions based on word of mouth on shopping sites rather than on information from the seller.
While third-party reviews are important, the existence of vendors who intentionally increase the number of good reviews has also become apparent and is becoming a problem, as is stealth marketing.
Also, in most cases where the distributor is not clear, there is no customer support contact, and the company is not responsible for the product.
Reliability can be checked based on the distributor's corporate information, size, history, expertise, and background of the representative, etc. If the distributor is a particularly well-known major company, it is considered less likely to handle inferior products.
It is important to choose products from major manufacturers, specialized manufacturers, and medical institutions.
3. IF YOU WANT TO EXPERIENCE MORE NMN, THE CONTENT IS ALSO IMPORTANT.
WE WILL SELECT PRODUCTS BASED ON THE PRODUCTS OF MANUFACTURERS WHOSE SAFETY IS ASSURED AND WHOSE PRODUCTS ARE TRUSTWORTHY, AND FINALLY, WE WILL SELECT PRODUCTS TO GET THE EXPERIENCE OF NMN.
MANY NMN SUPPLEMENTS PUT THE NMN CONTENT DIRECTLY INTO THE PRODUCT NAME.
For example, a product name such as NMN18000 often indicates that the NMN content is 18,000 mg.
NEVERTHELESS, BE SURE TO CHECK THE RAW MATERIALS AND TOTAL NMN CONTENT WHEN SELECTING A PRODUCT, AS SOME PRODUCTS HAVE A PRODUCT NAME THAT IS DIFFERENT FROM THE CONTENT.
SINCE THE BODY'S PRODUCTION OF NMN DECREASES WITH AGE, A HIGHER CAPACITY IS RECOMMENDED FOR OLDER PEOPLE.
Professor David A. Sinclair of Harvard University, known for his research on aging and rejuvenation, is 54 years old (as of January 2024) but professes to take 1,000 mg of NMN daily.
Of course, there are individual differences, so it is a good idea to try to find the right dosage for you, increasing the intake if you experience little sensation.
HOWEVER, THE INTAKE ADJUSTMENT IS ONLY POSSIBLE IF THE NMN SUPPLEMENT CONTAINS PURE NMN RAW MATERIALS.
PLEASE NOTE THAT THERE ARE PRODUCTS THAT ARE LABELED AS HIGH-PURITY BUT ACTUALLY CONTAIN NO NMN AT ALL.
In addition, although there are negative voices about taking large doses of more than 1,000 mg per day, in the U.S., NMN is in the Phase 1 to Phase 2 stage of safety and durability evaluation as a new drug, and it has been evaluated based on a 1,000 mg intake.
NOTES ON NMN PURITY
NMN SHOULD BE HIGHLY PURIFIED, BUT THERE ARE TWO CAVEATS THAT MUST BE OBSERVED.
a. Manufacturing method
NMN IS PRODUCED MAINLY BY THREE METHODS: CHEMICAL SYNTHESIS, YEAST METHOD, AND ENZYMATIC METHOD.
CHEMICALLY SYNTHESIZED NMN IS PRODUCED BY A CHEMICAL REACTION THAT DIFFERS FROM THE PROCESS AND COMPONENTS BY WHICH NMN IS ORIGINALLY PRODUCED IN THE BODY.
WHILE THE LOW COST OF PRODUCTION KEEPS THE SELLING PRICE OF SUPPLEMENTS LOW, IMPURITIES ARE PRODUCED AT THE SAME TIME AS NMN, AND THE RISK OF REMAINING INGREDIENTS CANNOT BE ELIMINATED EVEN IF THE PURITY OF NMN IS HIGH.
On the other hand, the yeast and enzyme methods have fewer such risks, but the products tend to be more expensive because of the high cost of production.
b. Price
Because of the above circumstances, higher-priced products can be an option in terms of safety, but supplements are more likely to be experienced when taken daily, which confronts the economic issue.
Conversely, in the case of inexpensive products, distrust of the manufacturing method and NMN content tends to remain, and the Asahi Shimbun investigation revealed that NMN itself was not detected in some products, especially those in the low price range of 1,000 yen to 5,000 yen.
This has made it clear that some consumers are losing money buying cheap goods.
This does not necessarily mean that you should choose the higher-priced ones, but you should also keep in mind the concern that there are good reasons for inexpensive ones.
summary
THERE ARE THREE KEY FACTORS IN SELECTING AN NMN SUPPLEMENT: SAFETY, TRANSPARENCY OF THE DISTRIBUTOR, AND CONTENT.
As for the content, as explained at the end of the article, there are some that "do not contain any," so it is recommended that you try the product in an amount that matches your own experience, while confirming the reliability of safety and purity based on the manufacturing method.
If you are interested in starting NMN supplementation or have any questions about NMN, please feel free to contact us.
We accept inquiries 24 hours a day at the following address.
