NMN is an abbreviation for nicotinamide mononucleotide, an ingredient that functions similarly to a vitamin in the body.
HOWEVER, NOT MANY PEOPLE KNOW WHAT EXACTLY NMN IS AND HOW IT EXERTS ITS ANTI-AGING EFFECTS. IT ALSO SEEMS THAT NOT MANY PEOPLE KNOW HOW TO TAKE NMN EFFECTIVELY AND FOR WHOM IT IS RECOMMENDED.
THIS ARTICLE THEREFORE EXPLAINS THE MECHANISM BY WHICH NMN EXERTS ITS ANTI-AGING EFFECT, AS WELL AS HOW TO EFFICIENTLY INCORPORATE NMN INTO THE BODY AND THE AGE GROUPS FOR WHICH WE PARTICULARLY RECOMMEND TAKING NMN.
WHAT IS NMN? WHY IS IT EFFECTIVE FOR ANTI-AGING?
NMN IS A COMPONENT FOUND IN THE BODIES OF ALL LIVING ORGANISMS, INCLUDING HUMANS. IT IS ALSO PRODUCED IN THE HUMAN BODY, BUT THE AMOUNT OF NMN IN THE BODY DECLINES WITH AGE, LEADING TO A DECLINE IN BODILY FUNCTIONS AND AFFECTING PHYSICAL CONDITIONS.
A COMPONENT CALLED NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE) PLAYS AN IMPORTANT ROLE IN THE ANTI-AGING ACTION OF NMN. NMN TAKEN INTO CELLS IS CONVERTED TO NAD+, A TYPE OF COENZYME, AND IS THOUGHT TO BE INVOLVED IN MAINTAINING BODILY FUNCTIONS AND ACTIVATING ANTI-AGING GENES.
LET US NOW LOOK MORE CLOSELY AT THE SPECIFIC MECHANISMS OF THE ANTI-AGING EFFECTS OF NMN.
Because the sirtuin gene is activated
NAD+, WHICH IS CONVERTED FROM NMN, ACTIVATES THE SIRTUIN GENE, ALSO KNOWN AS THE "LONGEVITY GENE" OR "REJUVENATION GENE.
SIRTUIN GENES ARE CLOSELY RELATED TO AGING AND LIFESPAN IN HUMANS. HUMANS HAVE SEVEN TYPES OF SIRTUIN GENES, AND NAD+ ACTIVATES ALL SEVEN TYPES OF SIRTUIN GENES. WHEN SIRTUIN GENES ARE ACTIVATED, THE DECLINE IN PHYSICAL AND COGNITIVE FUNCTIONS ASSOCIATED WITH AGING IS SUPPRESSED, AND A REJUVENATING EFFECT CAN BE EXPECTED.
SINCE THE HIGHER THE AMOUNT OF NAD+, THE MORE ACTIVATED THE SIRTUIN GENE IS, THE INTAKE OF ITS PRECURSOR, NMN, IS VERY IMPORTANT. IN FACT, INFINIXX'S OWN TESTS HAVE SHOWN THAT SIRTUIN GENE WAS SIGNIFICANTLY ACTIVATED IN A STUDY IN WHICH NMN WAS ADMINISTERED TO HUMANS FOR 3 MONTHS.
TO SUPPORT NAD+ PRODUCTION IN THE BODY
NAD+ IS A NUTRIENT THAT HELPS IN THE PRODUCTION OF ENERGY AND THE PREVENTION OF AGING, BUT IT HAS A LARGE MOLECULAR WEIGHT AND IS RARELY ABSORBED WHEN TAKEN DIRECTLY. ON THE OTHER HAND, NMN, A PRECURSOR OF NAD+, IS RAPIDLY ABSORBED INTO THE BLOOD AND CONVERTED TO NAD+ WHEN INGESTED.
SINCE NAD+ IN THE BODY DECREASES WITH AGE, NMN INTAKE IS EFFECTIVE IN INCREASING THE AMOUNT OF NAD+ IN THE BODY. IN OTHER WORDS, ACTIVE INTAKE OF NMN, WHICH SUPPORTS THE GENERATION OF NAD+, IS A VERY EFFECTIVE WAY TO OBTAIN ANTI-AGING EFFECTS.
HOW CAN I TAKE NMN?
SO HOW CAN WE CONSUME NMN?
NMN CAN BE TAKEN INTO THE BODY THROUGH FOOD, COSMETICS SUCH AS SERUMS, INTRAVENOUS INFUSIONS, AND SUPPLEMENTS. HOWEVER, IT IS BELIEVED THAT CONTINUOUS USE AND INGESTION ARE NECESSARY TO BRING OUT THE ANTI-AGING EFFECTS OF NMN.
HERE ARE THREE EASY WAYS TO CONSUME NMN THAT ARE EASY TO KEEP UP WITH.
Consume vegetables
NMN CAN ALSO BE OBTAINED FROM VEGETABLES, BEEF, SHRIMP, ETC. FOODS PARTICULARLY RICH IN NMN ARE VEGETABLES SUCH AS EDAMAME, BROCCOLI, AVOCADOS, AND TOMATOES.
However, the amount of NMN contained in food is negligible: even edamame, which is considered to be relatively rich in NMN, contains only 0.47 to 1.88 mg of NMN in 100 g of soybeans. To consume the recommended daily amount of 250 mg, one would have to eat about 82,500 edamame, weighing 53.2 kg. In addition, NMN is heat-sensitive, so if it is ingested from food, cooking should be avoided.
THUS, SINCE IT IS DIFFICULT TO SUPPLEMENT THE DAILY NMN REQUIREMENT THROUGH DIET ALONE, IT IS RECOMMENDED TO USE NMN IN COMBINATION WITH SUPPLEMENTS IF ONE EXPECTS ANTI-AGING EFFECTS.
https://www.infinixx.jp/journal/0012
Use cosmetics (serums)
EVEN WHEN NMN IS USED AS A COSMETIC, ITS ANTI-AGING EFFECT CAN BE EXPECTED.
ACCORDING TO A RECENTLY PUBLISHED REPORT, WHEN AN AQUEOUS NMN SOLUTION WAS APPLIED TO A HUMAN SKIN CULTURE MODEL, THE AMOUNT OF NMN IN THE CELLS INCREASED APPROXIMATELY 100-FOLD, AND THE AMOUNT OF NAD+ ALSO INCREASED APPROXIMATELY 4-FOLD. THIS RESULT CAN BE ASSUMED TO MEAN THAT NMN WAS ABSORBED BY SKIN CELLS AND METABOLIZED TO NAD+.
THIS IS NOT THE ONLY EFFECT OF NMN ON SKIN; IN MAY 2022, THE ANTI-MELANIN ACTION OF NMN WAS ALSO REPORTED. THIS STUDY REPORTED THAT NMN INHIBITED MELANIN PRODUCTION IN A HUMAN SKIN CULTURE MODEL CONTAINING AGED MELANOCYTES.
THEREFORE, EVEN WHEN NMN IS INCORPORATED INTO COSMETICS AND OTHER BEAUTY PRODUCTS AS A SERUM, A HIGH LEVEL OF ANTI-AGING ACTION CAN BE EXPECTED.
Use of supplements
IF YOU WANT TO EXPERIENCE YOUTHFULNESS NOT ONLY FROM THE SKIN, BUT ALSO FROM THE INSIDE OF YOUR BODY, SUPPLEMENTS ARE THE WAY TO GO. WITH SUPPLEMENTS, YOU DO NOT NEED TO CONSUME A LARGE AMOUNT OF NMN LIKE VEGETABLES. THEY CAN ALSO BE TAKEN ON THE GO, WITHOUT THE HASSLE OF GOING TO A MEDICAL FACILITY AS IS THE CASE WITH INTRAVENOUS INFUSIONS.
HOWEVER, THE PURITY AND CONTENT OF NMN IN SUPPLEMENTS VARY FROM MANUFACTURER TO MANUFACTURER. ABSORPTION RATES AND EFFECT DURATIONS ARE ALSO NOT THE SAME. UNFORTUNATELY, THERE ARE ALSO MANY INFERIOR PRODUCTS ON THE MARKET.
THEREFORE, IF YOU ARE LOOKING FOR BETTER EFFECTS, YOU MUST CHOOSE YOUR SUPPLEMENT CAREFULLY. IF YOU ARE NOT SURE WHICH PRODUCT TO CHOOSE, CHOOSE A PRODUCT FROM A MANUFACTURER THAT HAS WELL-DOCUMENTED OBJECTIVE PROOF OF NMN PURITY, CONTENT, AND INGREDIENT CONTENT.
IF YOU EXPECT NMN TO BE ANTI-AGING, START IN YOUR 40S AND 50S.
THE FOLLOWING SECTION DESCRIBES THE AGE GROUPS FOR WHICH NMN INTAKE IS PARTICULARLY RECOMMENDED AND WHY.
BASED ON THE RESULTS OF ANIMAL STUDIES, NMN IS NOT EXPECTED TO HAVE A CLEAR ANTI-AGING EFFECT WHEN TAKEN BY HEALTHY PEOPLE IN THEIR 20S AND 30S. SINCE NMN IS ALSO PRODUCED BY THE BODY, HEALTHY YOUNG PEOPLE ARE THOUGHT TO HAVE SUFFICIENT AMOUNTS OF NMN AND NAD+ WITHOUT SUPPLEMENTATION.
SO, AT WHAT AGE SHOULD WE START TAKING NMN TO EXPECT ITS ANTI-AGING EFFECTS?
ALTHOUGH THERE ARE INDIVIDUAL DIFFERENCES IN THIS REGARD, IT IS GENERALLY RECOMMENDED TO TAKE NAD+ IN ONE'S 40S OR 50S, WHEN THE AMOUNT OF NAD+ IN THE BODY BEGINS TO DECREASE AND VARIOUS AGING PHENOMENA BEGIN TO APPEAR, I.E., IN ONE'S 40S OR 50S.
IN A STUDY USING MICE, ANTI-AGING EFFECTS SUCH AS INCREASED PHYSICAL ACTIVITY WERE OBSERVED EVEN WHEN NMN WAS INGESTED BY ELDERLY MICE, WHO ARE EQUIVALENT TO HUMANS IN THEIR 70S. THEREFORE, ANTI-AGING EFFECTS MAY BE EXPECTED EVEN WHEN NMN IS INGESTED BY ELDERLY PEOPLE WHO ARE ALREADY SHOWING CHANGES DUE TO AGING.
HOWEVER, EACH PERSON WILL SHOW CHANGES WITH AGE IN A DIFFERENT WAY. IF YOU BEGIN TO NOTICE AGE-RELATED CHANGES, YOU MAY START TAKING NMN IN YOUR 30S OR SO.
summary
NMN IS A VITAMIN-LIKE SUBSTANCE THAT IS ALSO PRESENT IN THE HUMAN BODY, AND NAD+, WHICH IS PRODUCED FROM NMN, IS ESSENTIAL FOR NMN'S ANTI-AGING ACTION. NMN TAKEN INTO THE BODY IS QUICKLY CONVERTED INTO NAD+, WHICH ACTS ON THE SIRTUIN GENE AND EXERTS ITS ANTI-AGING EFFECTS.
HOWEVER, THE AMOUNT OF NMN IN THE BODY DECREASES WITH AGE, SO CONTINUOUS INTAKE IS NECESSARY TO MAINTAIN YOUTHFULNESS. HOWEVER, NMN CANNOT BE SUPPLEMENTED BY DIET ALONE. IF YOU WANT TO EFFICIENTLY CONSUME THE NECESSARY AMOUNT, WE RECOMMEND THE USE OF SUPPLEMENTS AND COSMETICS.
IT IS THOUGHT THAT PEOPLE IN THEIR 40S AND 50S, WHO BEGIN TO NOTICE AGE-RELATED CHANGES, ARE PARTICULARLY LIKELY TO EXPERIENCE THE ANTI-AGING EFFECTS OF NMN. HOWEVER, IT MAY BE POSSIBLE TO START TAKING NMN A LITTLE EARLIER AS AN ANTI-AGING MEASURE.
IF YOU FEEL "A LITTLE TIRED LATELY" OR "I MAY NOT BE ABLE TO BEAT THE CHANGES OF AGE ......," YOU MAY WANT TO CONSIDER TAKING NMN.
