1. NMN HAS NO SIDE EFFECTS AND IS SAFE TO TAKE!
Because NMN is a new ingredient, you may have concerns such as "Is it safe?" and "What about side effects?" NMN is a new ingredient, so you may have concerns about whether it is safe or not, or about side effects.
As it turns out, NMN has no side effects and can be safely ingested and applied to the skin.
At INFINIXX, we have conducted various tests and obtained data to ensure the safety of NMN.
Based on the data, we will show you why NMN can be safely ingested and applied to your skin.
1-1. ACUTE ORAL TOXICITY STUDIES AND CLINICAL TRIALS IN HUMANS DEMONSTRATE THE SAFETY OF NMN
To confirm the safety of NMN, INFINIXX conducted its own "acute toxicity test" and "human clinical study".
In the acute toxicity test, 2000 mg/kg of NMN was administered to mice, and no toxicity was observed. No abnormality was observed after 14 days of observation.
To further demonstrate the safety of NMN, a cumulative total of more than 22 clinical tests were conducted on humans, not mice, and no abnormality was observed here either.
From these results, it can be said that NMN is an ingredient that can be taken with peace of mind.
1-2. JOINT STUDY BETWEEN KEIO UNIVERSITY AND UNIVERSITY OF WASHINGTON ALSO CONCLUDES THAT NMN HAS NO SIDE EFFECTS.
A human clinical study conducted by Keio University and the University of Washington has also reported that NMN can be safely absorbed by our bodies.
This clinical study was conducted on 10 healthy men to determine if NMN can be safely administered to humans. The results were as follows
(1) Can be safely administered
(2) Metabolized in the body according to the dose administered
Also, at this time, there have been no reports of any side effects of any kind, either in humans or animals.
*Authors: J. Irie, E. Inagaki, M. Fujita, H. Nakatani, M. Mitsuishi, S. Yamaguchi, K. Yamashita, S. Shigaki, T. Ono, H. Yukioka, E. Okano, Y. Nabeshima, S. Imai, M. Yasui, K. Tsubota, H. Ito.
"Effects of oral nicotinamide mononucleotide administration on clinical parameters and nicotinamide metabolites in healthy Japanese men," Article.2019
1-3. In the case of supplements, "Self-Affirmed GRAS" certified NMN formulations are safe.
Self-Affirmed GRAS certification is a system in which toxicology experts in the U.S. objectively evaluate whether NMN is "safe to use in foods" according to the standards set by the U.S. Food and Drug Administration (FDA).
NMN raw materials that have obtained this "GRAS" certification can be said to be recognized as safe NMN for human consumption by the evaluation system of the United States, which is known as a major supplement country.
1-4. Choose skincare products that have undergone patch testing.
Many skincare products, including NMN serums, are designed to be safe and trouble-free for the skin, but if you want to use them with more peace of mind, you should choose those that have undergone a "patch test".
However, it is quite possible that abnormalities may occur depending on the user's constitution, physical condition, or the season, so it is important to test the product on an inconspicuous area such as the arm first.
2. THERE ARE THREE MAJOR WAYS TO SUPPLEMENT NMN
We have told you about the rejuvenating effects of NMN and that it is safe and without side effects, but how can it be supplemented?
There are three main ways.
- supplement
- Skin care such as serum
- NMN INFUSION
The following are the characteristics of each of these three methods.
2-1. EASY AND EFFICIENT NMN SUPPLEMENT
The current mainstream method of supplementing NMN is through supplements.
In addition to being easy to take, supplements are available from a variety of manufacturers, making it easy to choose the one that best suits your taste and budget.
However, it is necessary to examine supplements carefully when choosing one, as there are cases where low-priced supplements contain low amounts of NMN, fake or poor quality NMN raw materials, or in the worst cases, no NMN at all.
2-2. NMN-CONTAINING SERUMS AND OTHER SKIN CARE PRODUCTS ARE ALSO EFFECTIVE.
NMN has been shown to be effective when applied to the skin.
According to a joint research study conducted by Keio University and P&G Japan, when NMN solution was given to the stratum corneum side, the amount of NMN in skin cells increased approximately 100-fold, and the amount of NAD+ also increased 4-fold. This means that NMN serums and other skin care products are fully potent.
When choosing skincare products containing NMN, you should also pay attention to ingredients other than NMN.
It is a good idea to choose skincare products made with high-quality ingredients that bring out the effects of NMN, such as human stem cell extracts, growth factors, and aquaporins.
*Author：Kenyuki Hattori (Keio Univ.), Ryohei Aoyagi (Keio Univ.), Akira Date (P&G Japan), Yoshihiro Abe (Keio Univ.), Etsuomi Tamura (Keio Univ.).
"Effect of nicotinic acid amide mononucleotide (NMN), a precursor of NAD biosynthesis, on the differentiation of human skin epidermis," Thesis. 2013.
2-3. RECOMMENDED FOR THE PARTICULAR PERSON! NMN INFUSION AT CLINICS, ETC.
In addition to NMN supplements and NMN serums for home care, NMN infusion at clinics is also supported, especially by celebrities and those with a strong sense of beauty.
In general, IV infusion is absorbed more quickly and efficiently than supplements, so it is recommended for those who want to feel the effects of NMN quickly and who are able to regularly visit a clinic.
3. HOW TO CHOOSE NMN PRODUCTS
The market for NMN products is now a mixed bag, ranging from expensive to low-priced products. In general, it is safe to assume that the quality of the product is proportional to its selling price.
So, what exactly should we pay attention to when selecting NMN products?
Let us tell you the key points.
3-1. USING DOMESTICALLY PRODUCED NMN AND DISCLOSING RAW MATERIAL DATA
NMN is currently flooded with imitations in many Asian countries due to its scarcity.
One of the criteria for selecting a high-quality NMN is that it is "domestically produced.
Another criterion is whether the product has undergone a "raw material authenticity test" and discloses this information. The fact that the product has passed this test is the best proof that it is a genuine NMN.
Purity is also important, and you should choose the purest one possible.
To further assure safety, "radiation tests" and "a system that allows the user to determine authenticity at a glance" are also important points to consider when selecting NMN.
3-2. HIGH EFFICIENCY OF NMN ABSORPTION BY PROPRIETARY TECHNOLOGY
Another key factor in selecting NMN products is whether or not they have proprietary technologies and whether or not they have increased absorption efficiency.
Although NMN products are becoming more popular, genuine quality NMN raw materials are still precious and expensive. Therefore, the key is whether the product has a proprietary technology that allows it to be efficiently absorbed into the body and to be more effective when applied to the skin.
In the "body site absorption test" conducted by INFINIXX, the absorption efficiency of NMN in the stomach, sublingual region, and intestines was examined. As a result, a six-fold increase in efficiency was confirmed in the intestine when stomach absorption was used as the standard.
Based on this, it is recommended that NMN products be selected based on the following criteria: if they are supplements, they should be equipped with unique technology for intestinal absorption and long-lasting effect, and if they are skin care products, they should be rich in supportive ingredients.
＜Click here for detailed intestinal absorption test results.
3-3. MANUFACTURED IN GMP AND ISO CERTIFIED PLANTS
No matter how high the quality of NMN is, it is meaningless without a good environment for manufacturing supplements and skin care products.
When selecting NMN products, choose those that have "GMP certification" or "ISO certification" on the package.
GMP certification is a system that requires proper manufacturing and quality control Certification means that the product is safely made and maintained at a certain level of high quality in all processes, from receiving raw materials to manufacturing and shipping.
ISO certification is also a comprehensive management system that covers not only quality but also human resource training.
If NMN itself is of high quality and the manufacturing environment is also of good quality, it is considered a safe NMN product.
3-4. INFINIXX'S OWN NMN SELECTION CRITERIA "APPS™️
With the growing attention, many so-called counterfeit NMN products have started to appear on the market. Therefore, INFINIXX created the world's first standard for NMN quality, "APPS (™️).
APPS is an acronym for "A = Authenticity," "P = Purity," "S = Stability (quality stability)," and "S = S=Safety".
By selecting NMN products based on APPS, the system allows you to obtain 100% authentic quality and guaranteed safety.
<CLICK HERE FOR MORE INFORMATION ON "APPS (™️)" >.
summary
As mentioned above, NMN is a remarkable ingredient that can be safely ingested without side effects, but since NMN products on the market are a mixed bag, please take note of the selection points and choose the one that suits you best.
Please choose the right NMN product for you by taking NMN, which holds the key to youth, into your daily life with peace of mind and enjoy a life full of elasticity.
What is NMN anyway? What are its benefits? If you're wondering, check out
▶︎ "What is NMN, a hot ingredient that holds the key to preventing aging?" Check out the article at ◀︎
