NMN (NICOTINAMIDE MONONUCLEOTIDE) IS A VITAMIN-LIKE INGREDIENT ALSO FOUND IN VEGETABLES SUCH AS EDAMAME AND BROCCOLI. YOU MAY KNOW IT AS AN "ANTI-AGING INGREDIENT" BECAUSE IT ACTIVATES THE SIRTUIN GENE (ALSO KNOWN AS THE LONGEVITY GENE), WHICH IS CLOSELY RELATED TO AGING.
THE USE OF SUPPLEMENTS AND INTRAVENOUS INFUSION ARE WELL-KNOWN METHODS OF TAKING NMN INTO THE BODY. RECENTLY, MANY COSMETICS CONTAINING NMN ARE ALSO ON THE MARKET, WHICH HAS EXPANDED THE OPPORTUNITIES TO USE NMN MORE EASILY.
THIS ARTICLE WILL THEREFORE TAKE A CLOSER LOOK AT THE BEAUTY EFFECTS OF NMN, AND EXPLAIN SOME POINTS TO KEEP IN MIND WHEN SELECTING COSMETICS THAT CONTAIN NMN.
NMN COSMETICS? WHAT KIND OF COSMETIC EFFECT DOES IT HAVE?
FIRST, LET'S LOOK AT WHAT KIND OF COSMETIC EFFECTS CAN BE EXPECTED WHEN NMN IS INCORPORATED AS A COSMETIC PRODUCT.
NMN INTAKE SUPPORTS THE PRODUCTION OF NAD+.
WHEN NMN IS INGESTED THROUGH SUPPLEMENTS, INFUSIONS, OR COSMETICS, IT IS QUICKLY CONVERTED TO NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE), WHICH PLAYS A CENTRAL ROLE IN THE ANTI-AGING EFFECTS OF NMN AND IS ALSO ESSENTIAL FOR ENERGY PRODUCTION IN CELLS AND ACTIVATION OF THE SIRTUIN GENE.
ALTHOUGH NAD+ DECREASES WITH AGE, IT HAS BEEN SHOWN THAT THE AMOUNT OF NMN IN THE BODY CAN BE INCREASED BY INGESTING NMN, A PRECURSOR OF NAD+. IN FACT, A STUDY ON THE EFFECTS OF NMN SOLUTION APPLIED TO A HUMAN SKIN CULTURE MODEL REPORTED A 100-FOLD INCREASE IN THE AMOUNT OF NMN IN SKIN CELLS AND A 4-FOLD INCREASE IN THE AMOUNT OF NAD+.
INCREASED INTRACELLULAR NAD+ LEVELS STIMULATE ENERGY PRODUCTION AND SIRTUIN GENE ACTIVATION, WHICH MAY REDUCE VARIOUS AGE-RELATED CHANGES.
IF YOU INCREASE THE AMOUNT OF NAD+ IN YOUR CELLS BY INCORPORATING NMN INTO YOUR SKIN, YOU MAY BE ABLE TO CREATE FIRM, AGE-DEFYING SKIN.
Possibility of improving skin problems and metabolism
THE USE OF COSMETICS CONTAINING NMN IS BELIEVED TO HAVE A POSITIVE EFFECT ON IMPROVING SKIN PROBLEMS ASSOCIATED WITH AGING AND IMPROVING METABOLISM.
THE AFOREMENTIONED STUDY USING AQUEOUS NMN SOLUTION REVEALED THAT NMN APPLICATION ACTIVATES THE SIRTUIN GENE AND PROMOTES THE PRODUCTION OF NATURAL MOISTURIZING FACTORS. THEREFORE, THE RESEARCHERS CONCLUDED THAT THE APPLICATION OF NMN MAY PREVENT SKIN AGING.
CITATION: AUTHOR：KENYUKI HATTORI (KEIO UNIV.), RYOHEI AOYAGI (KEIO UNIV.), AKIRA DATE (P&G JAPAN), YOSHIHIRO ABE (KEIO UNIV.), ETSUOMI TAMURA (KEIO UNIV.). EFFECT OF NICOTINIC ACID AMIDE MONONUCLEOTIDE (NMN), A PRECURSOR OF NAD BIOSYNTHESIS, ON THE DIFFERENTIATION OF HUMAN SKIN EPIDERMIS" THESIS.2013
( http://nenkai.pharm.or.jp/133abst/30amD-216.pdf )
OTHER STUDIES USING MELANOCYTES HAVE SUGGESTED THAT NMN MAY SUPPRESS EXCESSIVE PIGMENTATION ASSOCIATED WITH AGING.
FURTHERMORE, SINCE NAD+ IS ALSO INVOLVED IN THE METABOLISM OF MANY CELLS, APPLICATION OF NMN MAY HELP IMPROVE SKIN PROBLEMS ASSOCIATED WITH DISTURBED METABOLISM.
Better absorption rate than food or supplements
THE COMPONENTS DESCRIBED ABOVE CAN BE SIMILARLY BENEFITED BY CONSUMING FOODS CONTAINING NMN IN THE DIET OR AS SUPPLEMENTS.
NEVERTHELESS, THE ORDER IN WHICH NUTRIENTS ARE ABSORBED HAS AN IMPACT ON WHY WE RECOMMEND NMN-BASED COSMETICS.
Nutrients taken in through food and supplements are consumed by the parts of the human body that are necessary for the activities of living, such as blood, brain, and muscles.
On the other hand, nutrients reach the skin and hair last.
HOWEVER, COSMETICS CAN BE USED TO MORE DIRECTLY ABSORB NMN INTO THE SKIN.
IN FACT, RESEARCH HAS SHOWN THAT WHEN NMN SERUM IS GIVEN TO THE STRATUM CORNEUM, THE AMOUNT OF NMN IN THE CELLS INCREASES APPROXIMATELY 100-FOLD, AND THE AMOUNT OF NAD+ ALSO INCREASES APPROXIMATELY 4-FOLD.
MANY NMN COSMETICS HAVE INFERIOR PRODUCTS.
NMN BECAME KNOWN IN JAPAN AROUND 2015. IN ADDITION, SINCE THE FOOD AND DRUG CLASSIFICATION WAS REVISED IN 2020 TO ALLOW NMN TO BE TREATED AS A "NON-MEDICAL PRODUCT," NUMEROUS MANUFACTURERS BEGAN TO FOCUS ON THE DEVELOPMENT AND MARKETING OF NMN PRODUCTS.
NMN, WITH ITS POTENTIAL ANTI-AGING PROPERTIES, IS AN ATTRACTIVE INGREDIENT FROM THE MANUFACTURER'S POINT OF VIEW, AND A VARIETY OF NMN PRODUCTS ARE NOW BEING DISTRIBUTED, INCLUDING SUPPLEMENTS, INTRAVENOUS INFUSIONS, AND COSMETICS.
HOWEVER, THERE ARE MANY NMN COSMETICS PRODUCTS THAT CAN ONLY BE DESCRIBED AS INFERIOR. IN FACT, IT IS SAID THAT ABOUT 70% OF NMN PRODUCTS CIRCULATING IN THE GLOBAL NMN MARKET ARE FAKE. IN ADDITION, RAW MATERIALS ARE EXPENSIVE, COSTING SEVERAL HUNDRED THOUSAND YEN PER KILOGRAM, AND THERE ARE MANY COMPANIES THAT SELL PRODUCTS WITH LOW NMN PURITY.
Therefore, one should be wary of cosmetics that are significantly underpriced.
TO AVOID PURCHASING INFERIOR PRODUCTS, BE SURE TO CHECK THE POINTS LISTED IN THE NEXT SECTION WHEN SELECTING NMN COSMETICS.
POINTS TO CONSIDER WHEN SELECTING NMN COSMETICS
HERE ARE SOME TIPS FOR CHOOSING NMN COSMETICS.
OF COURSE, IT IS ESSENTIAL TO CHECK THE CONTENT OF INGREDIENTS. INGREDIENT LABELS FOR COSMETICS ARE REQUIRED TO LIST INGREDIENTS IN THE ORDER OF THE HIGHEST TO LOWEST AMOUNTS. THEREFORE, IF YOU ARE LOOKING FOR HIGHER EFFICACY, CHOOSE THOSE WITH "NMN" OR "NICOTINAMIDE MONONUCLEOTIDE" LISTED AT THE TOP OF THE INGREDIENT LIST.
THE PURITY OF NMN IS ALSO IMPORTANT; THE QUALITY OF AN NMN PRODUCT IS PROPORTIONAL TO ITS PURITY. LOW PURITY MEANS THAT THERE ARE THAT MANY IMPURITIES IN THE PRODUCT, WHICH IS WHY IT IS NOT RECOMMENDED FROM A SAFETY STANDPOINT. IF POSSIBLE, WE RECOMMEND THAT YOU CHOOSE A PRODUCT THAT USES NMN RAW MATERIALS THAT HAVE BEEN TESTED FOR LETHAL SHOCK HAZARD AND ENDOTOXIN AND MEET SAFETY STANDARDS AT THE LEVEL OF INTRAVENOUS DRUG FORMULATIONS. SECTION LATER ON.
Some manufacturers present various certificates to promote their reliability, but having a certificate does not necessarily equate to high quality, because certificates can be easily forged. This is because certificates can be easily forged.
In fact, there are manufacturers who present forged or unreliable certificates. To avoid being misled by such fakes and to choose a product that is truly effective, please note the following points.
Whether the product is from a reliable manufacturer
Manufacturers whose official websites do not exist or products that do not display safety data should not be trusted. The same is true if the contact information is not clear. Do not buy from a manufacturer if you have even the slightest suspicion of their product.
It is also important to confirm whether the product has a proven sales track record and whether it has undergone clinical trials. If the product is made by a manufacturer that was originally involved in the production and sale of raw materials or cosmetics, you can buy it with more confidence.
Are the ingredients in the formula good for you?
WHEN PURCHASING NMN COSMETICS, ONE MUST ALSO PAY ATTENTION TO INGREDIENTS OTHER THAN NMN.
For example, parabens, mineral oil, synthetic colorants, synthetic fragrances, talc, silicone, and bergapten are common ingredients used in cosmetics, but they can cause skin problems.
Of course, not all products containing these are dangerous. However, considering their effects on the skin, it is ideal that they are not added (or kept to a minimum). If a product contains added preservatives, mineral oil, or synthetic coloring agents, choose a product that lists these ingredients at the back of the ingredient label.
Is there an inspection system in place for quality assurance?
MANUFACTURERS OF QUALITY NMN PRODUCTS CONDUCT THIRD-PARTY INSPECTIONS AND DISCLOSE THE RESULTS.
TYPICAL TESTS THAT GUARANTEE QUALITY AND SAFETY INCLUDE "RAW MATERIAL AUTHENTICITY TEST," "ACUTE TOXICITY TEST," "RADIATION TEST," AND "PATCH TEST FOR ALLERGY. IN PARTICULAR, SINCE NMN PRODUCTS ARE CONSIDERED TO BE OFTEN COUNTERFEIT, YOU CAN PURCHASE PRODUCTS FROM MANUFACTURERS WHO CONDUCT RAW MATERIAL AUTHENTICITY TESTS FOR EACH LOT WITH PEACE OF MIND.
Furthermore, products made in factories that meet Good Quality Practice (GQP) and Good Vigilance Practice (GVP) standards for quality control and safety control are even safer.
*THE SUPERVISOR IS NOT INVOLVED IN THE FOLLOWING HEADING "WHY NORDESTE IS THE BEST CHOICE FOR NMN COSMETICS".
WHY NORDESTE IS THE BEST CHOICE FOR NMN COSMETICS?
NMN COSMETICS ARE AVAILABLE FROM A VARIETY OF MANUFACTURERS.
THE NMN SERUM WE SELL IS SAFE AND SECURE BECAUSE IT IS THE RAW MATERIAL USED IN APPROXIMATELY 80% OF NMN INFUSIONS CONDUCTED IN JAPAN.
WE ALSO SELL A SKIN CARE LINE THAT INCLUDES NMN SERUM & MULTIFUNCTIONAL GEL.
HERE WE INTRODUCE THE FEATURES OF OUR SERUM AND MULTIFUNCTIONAL GEL, WHICH CONTAINS JAPAN'S FIRST LIPOSOMALIZED NMN, THREE TYPES OF HUMAN STEM CELL CULTURE FLUID, AND SEVEN TYPES OF FUNCTIONAL PEPTIDES.
UTILIZES HIGH-PURITY (99.9%) DOMESTIC NMN
BECAUSE NORDESTE PRODUCES NMN DOMESTICALLY FROM RAW MATERIALS, THERE IS ABSOLUTELY NO RISK OF CONTAMINATION WITH COUNTERFEIT NMN. IN ADDITION, WE PRODUCE NMN WITH THE HIGHEST PURITY OF 99.9%, WHICH IS AS PURE AS POSSIBLE, AND USE IT IN OUR COSMETICS AND OTHER NMN PRODUCTS. OF COURSE, THE PURITY VALUE IS BASED ON THE RESULTS OF TESTING BY A THIRD-PARTY ORGANIZATION IN JAPAN.
FURTHERMORE, NORDESTE CONDUCTS RAW MATERIAL AUTHENTICITY TESTS FOR EACH LOT, AND ONLY NMN THAT HAVE PASSED STRICT INSPECTIONS ARE USED IN ITS PRODUCTS. IN ADDITION, ANOTHER SIGNIFICANT FEATURE OF OUR PRODUCTS IS THAT WE VOLUNTARILY ESTABLISH SAFETY STANDARDS AT THE FORMULATION LEVEL AND CONDUCT INSPECTIONS.
MANUFACTURE OF PROPRIETARY NMN RAW MATERIALS THAT CAN BE STORED AT ROOM TEMPERATURE
NMN IS A VERY HEAT-SENSITIVE COMPONENT. THEREFORE, IT IS USUALLY DECOMPOSED AND THE NMN CONTENT DECREASES RAPIDLY UNLESS IT IS FROZEN.
HOWEVER, NORDESTE HAS SUCCEEDED IN MANUFACTURING HEAT-RESISTANT NMN RAW MATERIALS USING AN ORIGINAL SPECIAL MANUFACTURING METHOD. EVEN WHEN STORED AT ROOM TEMPERATURE, THE NMN CONTENT HARDLY DECREASES, SO ITS EFFECT IS MAINTAINED UNTIL THE VERY LAST DROP.
JAPAN'S FIRST LIPOSOMAL NMN SERUM
THE SERUM & GEL DEVELOPED BY NORDESTE IS THE FIRST COSMETIC PRODUCT IN JAPAN THAT CONTAINS LIPOSOMALIZED NMN.
LIPOSOME" IS A TECHNOLOGY THAT LOCKS BEAUTY INGREDIENTS INCLUDING NMN IN CAPSULES MADE OF PHOSPHOLIPIDS, WHICH ARE EASILY ABSORBED BY HUMAN SKIN, AND DELIVERS THEM TO THE STRATUM CORNEUM. LIPOSOMALIZED BEAUTY INGREDIENTS ENABLE ACTIVE INGREDIENTS TO PERMEATE INTO THE STRATUM CORNEUM IN A FRESH STATE, MAKING IT EASIER TO FEEL THE EFFECTS OF NMN.
ANOTHER KEY FEATURE OF OUR SERUM & GEL IS THAT IT CONTAINS 7 TYPES OF BIO-BASED PEPTIDES, 3 TYPES OF HUMAN STEM CELL CULTURE FLUID, AND 2 SYNERGISTIC INGREDIENTS THAT BRING OUT THE EFFECTS OF NMN. THIRTEEN ACTIVE INGREDIENTS ENCASED IN A LIPOSOME MEMBRANE WORK ON THE SKIN AT THE CELLULAR LEVEL TO SUPPORT THE CREATION OF YOUTHFUL, BEAUTIFUL SKIN.
CONTAINS 12 NUTRIENTS OTHER THAN NMN
Nordeste's serums & gels contain the following 12 nutrients to help bring out the skin's natural radiance.
Human recombinant polypeptide-66, human recombinant polypeptide-67, dicotinoyl hexapeptide-44 (Prospin), and synthetic human recombinant polypeptide-64, which condition the skin.
Human recombinant oligopeptide 1, synthetic human recombinant polypeptide 16, and synthetic human recombinant polypeptide 31, which support cell proliferation.
Human amniotic fluid, human bone marrow stem cell culture medium, and human fibroblast culture medium support skin regeneration.
DIMETHYLAMINOETHANOL TARTRATE" AND "ALLANTOIN" MAXIMALLY SUPPORT THE EFFECTS OF NMN.
THESE AND A TOTAL OF 13 OTHER NUTRIENTS, INCLUDING NMN, PROVIDE MAXIMUM SUPPORT FOR BRINGING OUT THE NATURAL ATTRACTIVENESS OF THE SKIN.
summary
NMN IS A NUTRIENT WITH POTENTIAL ANTI-AGING EFFECTS. NMN TAKEN INTO CELLS IS CONVERTED TO NAD+, WHICH PROMOTES ENERGY PRODUCTION AND ACTIVATION OF THE SIRTUIN GENE. RECENTLY, RESEARCH RESULTS ON THE COSMETIC EFFECTS OF NMN HAVE BEEN REPORTED ONE AFTER ANOTHER, AND THE NEED FOR NMN AS A COSMETIC INGREDIENT IS EXPECTED TO INCREASE FURTHER IN THE FUTURE.
HOWEVER, THERE ARE MANY INFERIOR NMN COSMETICS. TO AVOID COUNTERFEIT PRODUCTS OR PRODUCTS WITH QUESTIONABLE SAFETY, BEFORE PURCHASING, BE SURE TO CHECK THE PURITY AND AMOUNT OF NMN IN THE PRODUCT AND WHETHER IT HAS BEEN PROPERLY TESTED BY A THIRD-PARTY ORGANIZATION.
NMN COSMETICS ARE NOT INEXPENSIVE, BUT THEY ARE WELL WORTH THE PRICE, AND WITH NMN COSMETICS, YOU WILL HAVE GLAMOROUS SKIN THAT IS THE ENVY OF ALL.
