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Research

No. 1 NMN reagent market share
"N-Pro Med™️"

N-Pro Med®︎", No.1 share of NMN reagent raw materials

80%* share of the medical institution market, by far the preferred NMN for professionals* according to TPC Marketing Research, Inc.

We offer "N-Pro Med®︎," an NMN research reagent raw material that meets the strict standards required by professionals at medical and research institutions. N-Pro Med®︎" is the only NMN research reagent raw material used in research papers in which the safety and efficacy of intravenous (IV) administration to humans were confirmed*.
*As of September 2022, according to our own research.

caution

The products manufactured by other companies have only the same level of quality standards as food powder raw materials, and we cannot dispel concerns that they do not take the necessary steps for reagents, such as Authenticity, Purity, Stability, and Safety (sterilization process).

NMN REAGENT RAW MATERIAL USED IN THE WORLD'S ONLY RESEARCH PAPER THAT CONFIRMED THE SAFETY AND EFFICACY OF INTRAVENOUS ADMINISTRATION TO HUMANS

N-Pro Med®︎" has been used as a research reagent raw material in the following studies

  • Prof. Akinobu Goto and his research group (Hyogo Medical University School of Medicine)

    Article Abstract
    Examines the safety of intravenous administration of 300 mg of NMN. Intravenous NMN administration appears to be safe and beneficial.

    Efficacy
    Safety of intravenous administration of 300 mg of NMN.
    Intravenous NMN administration is considered safe and beneficial.
    ・Improved blood longevity molecule NAD+ level by about 20% (see NAD+ level graph)
    ・Improved sleep quality
    ・Blood fat (TG level) decreased by about 75% (see TG level graph)
    ・Improved TG level may lead to prevention and treatment of fatty liver and diabetes-related diseases

    TG LEVEL GRAPH
    NAD+ LEVEL GRAPH
  • Prof. Yoshihiro Uto and his research group (Graduate School of Decision Science and Technology, The University of Tokushima)

    JOINT RESEARCH ON ANTI-AGING EFFECTS OF NMN USING HUMAN SENESCENT CELLS, SENESCENT MICE, AND COMPANION ANIMALS, AND ANALYSIS AND CLARIFICATION OF ITS MECHANISM OF ACTION

  • Associate Professor Tetsuya Hosooka and his research group (Faculty of Food and Nutritional Sciences, University of Shizuoka)

    COLLABORATIVE RESEARCH TO ELUCIDATE THE EFFECTS AND MECHANISMS OF NMN ON AGE-RELATED MUSCLE ATROPHY AND OBESITY


    [Pubmed]
    Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes
    Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes
    ‍https://pubmed.ncbi.nlm.nih.gov/37144119/
    ‍‍https ://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151261/ (full text)

  • Associate Professor Tomohiro Osaki and his research group (Department of Collaborative Veterinary Medicine, Faculty of Agriculture, Tottori University)

    JOINT RESEARCH ON ANTI-AGING EFFECTS OF NMN USING HUMAN SENESCENT CELLS, SENESCENT MICE, AND COMPANION ANIMALS, AND ANALYSIS AND CLARIFICATION OF ITS MECHANISM OF ACTION

Quality Control System

N-Pro Med™️" is manufactured and controlled under a strict quality maintenance system.

Authenticity
Quality is controlled by producing NMN from raw materials in Japan.
There are two types of NMN: α-NMN and β-NMN. β-NMN is the one that is produced in the human body and has been confirmed to be safe and useful for humans.
N-Pro Med™️" is 100% β-NMN*.
*Inspection organization: Japan Food Analysis Center

Purity
The highest purity of 99.9%* is achieved through a special purification process.
*Inspection organization : Japan Food Inspection
Test method: High performance liquid chromatography

Stability (stability )
Stability quality (thermal decomposition) test*.

*Inspection organization : Nordeste Corporation
Test method: High performance liquid chromatography for NMN decay from 0 to 3 months at 4°C, 25°C, and 40°C, respectively

Safety
Highly safe NMN that can meet the Japanese Pharmacopoeia standard values* (intravenous administration).
*Inspection organization: Japan Food Analysis Center
Test method: Colorimetric method

Ingredient Information

β-Nicotinamide mononucleotide
β-Nicotinamide mononucleotide


β-Nicotinamide mononucleotide is an intermediate metabolite of the coenzyme NAD+, which is present in all living species. N-Pro Med®︎" is a research reagent raw material for purified β-Nicotinamide mononucleotide.
CAS No: 1094-61-7
Chemical formula: C11H15N2O8P
Structural formula:

〜Abe Yoando Pharmaceuticals and Medical

As a health care company that has been working closely with health for 290 years, we provide domestically produced and high-purity NMN. We contribute to the future of health and medicine through academic quality NMN trusted by medical and research institutions.
N-Pro Med™️" is a raw material (research reagent) for medical and research institutions and is not sold to general consumers.
For ‍
inquiries, please use the following address.
E-mail address : info@abeyoando.co.jp