research
Research
NMN ARTICLE ARCHIVE
Research on NMN and sirtuin genes is advancing rapidly, with new research papers being reported every month.
Here you can read the latest research papers in machine-translated Japanese.
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publication date
Title of paper (original)
Title of paper (automatic translation)
Name of author(s) of paper
category
original
automatic, machine translation
publication date
2014-06-06
Title of paper (original)
Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion
Title of paper (automatic translation)
NICOTINAMIDE MONONUCLEOTIDE, AN INTERMEDIATE IN NAD + SYNTHESIS, PROTECTS THE HEART FROM ISCHEMIA AND REPERFUSION
Author Name
Takanobu Yamamoto et al.
category
Other
publication date
2014-06-01
Title of paper (original)
Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
Title of paper (automatic translation)
EFFECTIVE TREATMENT OF MITOCHONDRIAL MYOPATHY WITH NICOTINAMIDE RIBOSIDE, A VITAMIN B 3
Author Name
Nahid A Khan et al.
category
Other
publication date
2014-05-31
Title of paper (original)
Effect of exercise intensity on post-exercise oxygen consumption and heart rate recovery
Title of paper (automatic translation)
Effect of exercise intensity on post-exercise oxygen consumption and heart rate recovery
Author Name
Theresa N Mann et al.
category
Other
publication date
2014-05-12
Title of paper (original)
SIRT2 induces the checkpoint kinase BubR1 to increase lifespan
Title of paper (automatic translation)
SIRT2 induces checkpoint kinase BubR1 to extend life span
Author Name
David Sinclair et al.
category
Aging and Rejuvenation
publication date
2014-05-08
Title of paper (original)
Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging
Title of paper (automatic translation)
Specific excision of Nampt in adult neural stem cells recapitulates their functional defects during aging
Author Name
Shinichiro Imai, et al.
category
Aging and Rejuvenation
publication date
2014-05-08
Title of paper (original)
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease
Title of paper (automatic translation)
NAD(+)-dependent activation of Sirt1 modifies the phenotype of a mouse model of mitochondrial disease
Author Name
Raffaele Cerutti et al.
category
Other
publication date
2014-04-29
Title of paper (original)
NAD+ and sirtuins in aging and disease
Title of paper (automatic translation)
NAD + AND SIRTUINS IN AGING AND DISEASE
Author Name
Shinichiro Imai, et al.
category
Aging and Rejuvenation
publication date
2014-02-01
Title of paper (original)
Partial reversal of skeletal muscle aging by restoration of normal NAD? levels
Title of paper (automatic translation)
PARTIAL REVERSAL OF SKELETAL MUSCLE AGING BY RESTORATION OF NORMAL NAD? LEVELS
Author Name
Andrew R Mendelsohn et al.
category
Aging and Rejuvenation
publication date
2013-12-19
Title of paper (original)
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
Title of paper (automatic translation)
DEBILITATING NAD+ INDUCES A PSEUDOHYPOXIC STATE THAT DISRUPTS NUCLEAR-MITOCHONDRIAL COMMUNICATION DURING AGING
Author Name
David Sinclair et al.
category
Aging and Rejuvenation
oxidation
publication date
2013-11-01
Title of paper (original)
Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotection
Title of paper (automatic translation)
NICOTINAMIDE RIBOSIDE, A MICRONUTRIENT IN FOODS, AFFECTS ENERGY METABOLISM AND NEUROPROTECTION VITAMIN B3
Author Name
Yuling Chi et al.
category
Other
publication date
2013-10-18
Title of paper (original)
Ketone bodies as signaling metabolites
Title of paper (automatic translation)
Ketones as signaling metabolites
Author Name
John C. Newman et al.
category
Aging and Rejuvenation
publication date
2013-09-19
Title of paper (original)
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice
Title of paper (automatic translation)
CIRCADIAN CLOCK NAD + CYCLE PROMOTES OXIDATIVE METABOLISM IN MOUSE MITOCHONDRIA
Author Name
Clara Bien Peek et al.
category
oxidation
publication date
2013-09-01
Title of paper (original)
The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and aging
Title of paper (automatic translation)
IMPORTANCE OF NAMPT / NAD / SIRT1 IN THE SYSTEMIC REGULATION OF METABOLISM AND AGING
Author Name
Shinichiro Imai, et al.
category
Aging and Rejuvenation
glycosuria
publication date
2013-08-06
Title of paper (original)
Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure
Title of paper (automatic translation)
MITOCHONDRIAL COMPLEX I DEFICIENCY INCREASES PROTEIN ACETYLATION AND PROMOTES HEART FAILURE
Author Name
Georgios Karamanlidis et al.
category
Other
publication date
2013-07-18
Title of paper (original)
The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Title of paper (automatic translation)
THE NAD(+)/SIRTUIN PATHWAY REGULATES LIFESPAN THROUGH ACTIVATION OF MITOCHONDRIAL UPR AND FOXO SIGNALING
Author Name
Laurent Mouchiroud et al.
category
Aging and Rejuvenation
publication date
2013-02-14
Title of paper (original)
Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation
Title of paper (automatic translation)
The antidiabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation
Author Name
Khang Wei Ong et al.
category
Other
publication date
2013-02-08
Title of paper (original)
Ketone body metabolism and cardiovascular disease
Title of paper (automatic translation)
Ketone metabolism and cardiovascular disease
Author Name
David G Cotter et al.
category
obesity
publication date
2013-01-09
Title of paper (original)
Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models
Title of paper (automatic translation)
Nicotinamide riboside restores cognition through growth factor-activated receptor-γ coactivator 1α-regulated β-secretase 1 degradation and upregulation of mitochondrial gene expression in a mouse model of Alzheimer's disease
Author Name
Bing Gong et al.
category
recognition
oxidation
publication date
2012-10-23
Title of paper (original)
NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy
Title of paper (automatic translation)
NAD + BIOSYNTHESIS IMPROVES ZEBRAFISH MODEL OF MUSCULAR DYSTROPHY
Author Name
Michelle F Goody et al.
category
Other
publication date
2012-09-11
Title of paper (original)
Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice mice
Title of paper (automatic translation)
LEUCINE SUPPLEMENTATION INCREASES SIRT1 EXPRESSION AND PREVENTS MITOCHONDRIAL DYSFUNCTION AND METABOLIC DISTURBANCES IN HIGH-FAT DIET-INDUCED OBESE MICE
Author Name
Hongliang Li et al.
category
obesity
publication date
2012-07-21
Title of paper (original)
The dynamic regulation of NAD metabolism in mitochondria
Title of paper (automatic translation)
DYNAMIC REGULATION OF NAD METABOLISM IN MITOCHONDRIA
Author Name
Shinichiro Imai, et al.
category
Other
publication date
2012-06-06
Title of paper (original)
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
Title of paper (automatic translation)
NAD + PRECURSOR NICOTINAMIDE RIBOSIDE ENHANCES OXIDATIVE METABOLISM AND PROTECTS AGAINST OBESITY CAUSED BY A HIGH-FAT DIET
Author Name
Carles Cant?
category
oxidation
Aging and Rejuvenation
publication date
2012-04-09
Title of paper (original)
The ketogenic diet as a treatment paradigm for diverse neurological disorders
Title of paper (automatic translation)
Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders
Author Name
Carl E. Stafstrom et al.
category
Other
publication date
2011-10-05
Title of paper (original)
Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
Title of paper (automatic translation)
NICOTINAMIDE MONONUCLEOTIDE, AN IMPORTANT NAD+ INTERMEDIATE, TREATS THE PATHOPHYSIOLOGY OF DIET- AND AGE-RELATED DIABETES IN MICE
Author Name
Shinichiro Imai, et al.
category
glycosuria
Aging and Rejuvenation
publication date
2011-09-01
Title of paper (original)
A 45-minute vigorous exercise bout increases metabolic rate for 14 hours
Title of paper (automatic translation)
45 minutes of vigorous exercise increases metabolic rate over 14 hours
Author Name
Amy M Knab et al.
category
obesity
publication date
2011-06-20
Title of paper (original)
The effect of the Spanish Ketogenic Mediterranean Diet on nonalcoholic fatty liver disease: a pilot study
Title of paper (automatic translation)
Effects of the Spanish Ketogenic Mediterranean Diet on Nonalcoholic Fatty Liver Disease: A Pilot Study
Author Name
Joaqu?n P?rez-Guisado et al.
category
obesity
publication date
2011-06-17
Title of paper (original)
NAD blocks high glucose induced mesangial hypertrophy via activation of the sirtuins-AMPK-mTOR pathway
Title of paper (automatic translation)
NAD blocks high glucose-induced mesangial hypertrophy via activation of the sirtuin AMPK-mTOR pathway
Author Name
Li Zhuo et al.
category
Other
publication date
2011-04-06
Title of paper (original)
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
Title of paper (automatic translation)
PARP-1 INHIBITION INCREASES MITOCHONDRIAL METABOLISM VIA SIRT1 ACTIVATION
Author Name
P?ter Bai et al.
category
Other
publication date
2011-01-01
Title of paper (original)
How to Know if You're Pre-Diabetic - Life Extension
Title of paper (automatic translation)
Are we all pre-diabetic?
Author Name
Kirk Stokel. et al.
category
glycosuria
Aging and Rejuvenation
publication date
2010-04-16
Title of paper (original)
Extending healthy life span--from yeast to humans
Title of paper (automatic translation)
Extends healthy life span from yeast to humans
Author Name
Luigi Fontana et al.
category
glycosuria
Aging and Rejuvenation
publication date
2010-03-03
Title of paper (original)
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
Title of paper (automatic translation)
INTERDEPENDENCE OF AMPK AND SIRT1 FOR METABOLIC ADAPTATION TO FASTING AND EXERCISE IN SKELETAL MUSCLE.
Author Name
Carles Cant?
category
Other
publication date
2009-08-29
Title of paper (original)
Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity
Title of paper (automatic translation)
EXTRACELLULAR PBEF / NAMPT / VISFATIN ACTIVATES INFLAMMATION-INDUCED SIGNALING IN HUMAN VASCULAR SMOOTH MUSCLE CELLS VIA NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE ACTIVITY
Author Name
T. Romacho et al.
category
Other
publication date
2009-05-16
Title of paper (original)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme
Title of paper (automatic translation)
Nicotinamide / Nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme
Author Name
Rong Grace Zhai et al.
category
Other
publication date
2009-04-23
Title of paper (original)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Title of paper (automatic translation)
AMPK REGULATES ENERGY EXPENDITURE BY MODULATING NAD+ METABOLISM AND SIRT1 ACTIVITY
Author Name
Carles Cant?
category
Other
publication date
2009-02-05
Title of paper (original)
The role of NAD biosynthesis in plant development and stress responses
Title of paper (automatic translation)
ROLE OF NAD BIOSYNTHESIS IN PLANT DEVELOPMENT AND STRESS RESPONSE
Author Name
Shin-nosuke Hashida et al.
category
Other
publication date
2008-12-26
Title of paper (original)
Nampt: linking NAD biology, metabolism and cancer
Title of paper (automatic translation)
NAMPT: NAD? S BIOLOGY, METABOLISM, AND CANCER.
Author Name
Shinichiro Imai, et al.
category
glycosuria
publication date
2008-10-24
Title of paper (original)
Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide
Title of paper (automatic translation)
Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotides.
Author Name
Pei Wang et al.
category
Other
publication date
2008-09-25
Title of paper (original)
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies
Title of paper (automatic translation)
Caloric restriction, ketone diet therapy, and neuroprotective properties of ketones
Author Name
Marwan Maalouf et al.
category
Other
publication date
2008-06-01
Title of paper (original)
Normal fasting plasma glucose and risk of type 2 diabetes diagnosis
Title of paper (automatic translation)
Normal fasting blood glucose and risk of type 2 diabetes diagnosis
Author Name
Gregory A Nichols et al.
category
glycosuria
publication date
2008-04-12
Title of paper (original)
Neuroendocrine factors in the regulation of inflammation: excessive adiposity and calorie restriction
Title of paper (automatic translation)
Neuroendocrine factors in the regulation of inflammation: excessive adipocytes and caloric restriction
Author Name
Luigi Fontana
category
obesity
publication date
2007-11-01
Title of paper (original)
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme
Title of paper (automatic translation)
Nampt / PBEF / visfatin regulates beta cell insulin secretion as a systemic NAD biosynthetic enzyme
Author Name
Shinichiro Imai, et al.
category
Other
publication date
2007-05-04
Title of paper (original)
Vitamins and aging: pathways to NAD+ synthesis
Title of paper (automatic translation)
VITAMINS AND AGING: PATHWAYS TO NAD + SYNTHESIS
Author Name
John M. Denu
category
Aging and Rejuvenation
publication date
2007-02-13
Title of paper (original)
A high-fat, ketogenic diet induces a unique metabolic state in mice
Title of paper (automatic translation)
High-fat, ketone-producing diets induce a unique metabolic state in mice
Author Name
Adam R Kennedy et al.
category
obesity
oxidation
publication date
2006-08-16
Title of paper (original)
Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
Title of paper (automatic translation)
Stimulation of the nicotinamide adenine dinucleotide biosynthetic pathway delays axonal degeneration after axotomy
Author Name
Yo Sasaki et al.
category
Other
publication date
2005-08-23
Title of paper (original)
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
Title of paper (automatic translation)
Intracellular compartmentalization and differential catalytic properties of three human nicotinamide mononucleotide adenylyltransferase isoforms.
Author Name
Felicitas Berger et al.
category
Other
publication date
2004-05-14
Title of paper (original)
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
Title of paper (automatic translation)
DISCOVERY OF NICOTINAMIDE RIBOSIDE AS A NUTRIENT AND CONSERVED NRK GENE ESTABLISHES AN INDEPENDENT PATHWAY FOR THE PRECIS HANDLER FOR NAD + IN FUNGI AND HUMANS
Author Name
Pawel Bieganowski et al.
category
Aging and Rejuvenation
publication date
2004-03-01
Title of paper (original)
The new life of a centenarian: signalling functions of NAD(P)
Title of paper (automatic translation)
A NEW LIFE AT 100: SIGNALING FUNCTIONS OF NAD
Author Name
Felicitas Berger et al.
category
Aging and Rejuvenation
oxidation
publication date
2003-07-01
Title of paper (original)
Reconstructing eukaryotic NAD metabolism
Title of paper (automatic translation)
RECONSTRUCTING EUKARYOTIC NAD METABOLISM
Author Name
Anthony Rongvaux et al.
category
Other
publication date
2003-05-22
Title of paper (original)
A randomized trial of a low-carbohydrate diet for obesity
Title of paper (automatic translation)
Randomized Trial of Low Carbohydrate Diet for Obesity
Author Name
Gary D Foster et al.
category
obesity
publication date
2003-04-01
Title of paper (original)
Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease
Title of paper (automatic translation)
Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, lifespan and disease
Author Name
Su-Ju Lin et al.
category
Aging and Rejuvenation
publication date
2001-03-09
Title of paper (original)
Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis
Title of paper (automatic translation)
CHARACTERIZATION OF RECOMBINANT HUMAN NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE (NMNAT), AN ESSENTIAL NUCLEOENZYME FOR NAD SYNTHESIS
Author Name
M Schweiger et al.
category
oxidation
publication date
2000-07-01
Title of paper (original)
Effects of high-intensity resistance training on untrained older men. II. muscle fiber characteristics and nucleo-cytoplasmic relationships
Title of paper (automatic translation)
EFFECTS OF HIGH-INTENSITY RESISTANCE TRAINING ON UNTRAINED OLDER ADULTS. II. MUSCLE FIBER CHARACTERISTICS AND NUCLEUS-CYTOPLASM RELATIONSHIPS.
Author Name
R S Hikida et al.
category
Aging and Rejuvenation
publication date
1999-06-24
Title of paper (original)
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP- ribosyltransferase activity
Title of paper (automatic translation)
Characterization of five human cDNAs homologous to the yeast SIR2 gene: Sir2-like protein (sirtuin) metabolizes NAD and may have protein ADP-ribosyltransferase activity
Author Name
Roy A.Frye
category
Aging and Rejuvenation
publication date
1997-01-01
Title of paper (original)
Determining NAD synthesis in erythrocytes
Title of paper (automatic translation)
DETERMINATION OF NAD SYNTHESIS IN ERYTHROCYTES
Author Name
Vanna Micheli et al.
category
Other
publication date
1993-09-01
Title of paper (original)
Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide (NADPH)-phosphate phosphate (NADPH)-dependent oxidase
Title of paper (automatic translation)
Oxygen radicals as second messengers of monocyte chemoattractant protein JE / MCP-1 and monocyte colony-stimulating factor CSF-1 expression in response to tumor necrosis factor-α and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase
Author Name
J A Satriano et al.
category
Other
publication date
1993-03-01
Title of paper (original)
Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in the temporal lobe of schizophrenics implies anomalous cortical development
Title of paper (automatic translation)
Distorted distribution of nicotinamide adenine dinucleotide phosphate diaphorase neurons in the temporal lobe of schizophrenia indicates abnormal cortical development
Author Name
Schahram Akbarian et al.
category
Other
publication date
1992-05-01
Title of paper (original)
Carbohydrate restriction regulates the adaptive response to fasting
Title of paper (automatic translation)
Carbohydrate restriction modulates adaptive responses to fasting
Author Name
S. Klein et al.
category
Other
publication date
1987-04-01
Title of paper (original)
Metabolism of nicotinamide mononucleotide in beef liver
Title of paper (automatic translation)
Metabolism of nicotinamide mononucleotides in bovine liver
Author Name
Tadayoshi Imai et al.
category
Other
publication date
1986-04-01
Title of paper (original)
Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide
Title of paper (automatic translation)
OXIDATIVE DAMAGE TO CELLS; DNA STRAND BREAKS ACTIVATE POLYADENOSINE DIPHOSPHATE - RIBOSE POLYMERASE, LEADING TO DEPLETION OF NICOTINAMIDE ADENINE DINUCLEOTIDE
Author Name
I U Schraufstatter etc.
category
oxidation
publication date
1984-12-01
Title of paper (original)
Degradation of NAD by synaptosomes and its inhibition by nicotinamide mononucleotide: implications for the role of NAD as a synaptic modulator
Title of paper (automatic translation)
DEGRADATION OF NAD BY SYNAPTOSOMES AND ITS INHIBITION BY NICOTINAMIDE MONONUCLEOTIDES: IMPLICATIONS FOR THE ROLE OF NAD AS A SYNAPTIC MODULATOR.
Author Name
C. R. Snell et al.
category
Other
publication date
1983-02-01
Title of paper (original)
Digestion and absorption of NAD by the small intestine of the rat
Title of paper (automatic translation)
DIGESTION AND ABSORPTION OF NAD BY THE SMALL INTESTINE OF RATS
Author Name
C J Gross et al.
category
Other
publication date
1980-01-01
Title of paper (original)
Physiological roles of ketone bodies as substrates and signals in mammalian tissues
Title of paper (automatic translation)
Physiological role of ketone bodies as substrates and signals in mammalian tissues.
Author Name
A M Robinson et al.
category
publication date
1972-07-01
Title of paper (original)
Levels of nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide in facultative bacteria and the effect of oxygen
Title of paper (automatic translation)
Nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide levels in commensal bacteria and the effect of oxygen
Author Name
Julian W. T. Wimpenny et al.
category
Other
publication date
1969-03-01
Title of paper (original)
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates substrates
Title of paper (automatic translation)
STUDY OF THE RATE OF REDUCTION OF HEPATIC MICROSOMAL CYTOCHROME P-450 BY REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE: INFLUENCE OF DRUG SUBSTRATES.
Author Name
PHILIPPE L. GIGON ET AL.
category
publication date
1968-12-13
Title of paper (original)
Deficiency of Reduced Nicotinamide-Adenine Dinucleotide Oxidase in Chronic Granulomatous Disease
Title of paper (automatic translation)
Nicotinamide - adenine dinucleotide oxidase deficiency in chronic granulomatosis
Author Name
Robert L. Baehner et al.
category
Other
publication date
1968-03-05
Title of paper (original)
NAD synthesis in animal tissues
Title of paper (automatic translation)
NAD SYNTHESIS IN ANIMAL TISSUES
Author Name
L. S. DIETRICH ET AL.
category
