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HYOGO MEDICAL UNIVERSITY CONFIRMS SAFETY IN HUMAN CLINICAL TRIAL WITH INTRAVENOUS NMN 300 MG

2023-02-17

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UNTIL NOW, MANY HUMAN CLINICAL STUDIES ON THE SAFETY OF ORAL INTAKE OF NMN HAVE BEEN REPORTED IN VARIOUS COUNTRIES AROUND THE WORLD, BUT THE EFFICACY AND SAFETY OF INTRAVENOUS ADMINISTRATION HAD NOT BEEN CONFIRMED. IN 2022, HYOGO MEDICAL UNIVERSITY REPORTED ON THE SAFETY OF INTRAVENOUS ADMINISTRATION OF 300 MG OF NMN IN HUMAN CLINICAL TRIALS. THIS REPORT SUGGESTS NEW POSSIBILITIES FOR NMN.

Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals"

Kimura S, et al. Cureus. 2022 Sep; 14(9): e28812. doi:10.7759/cureus.28812

NICOTINAMIDE MONONUCLEOTIDE (NMN) IS SAFELY METABOLIZED AND SIGNIFICANTLY LOWERS BLOOD TRIGLYCERIDE LEVELS IN HEALTHY INDIVIDUALS."

■ Thesis Outline

THE SAFETY OF INTRAVENOUS ADMINISTRATION OF 300 MG OF NMN BY INFUSION WAS TESTED AND FOUND TO HAVE NO EFFECT ON ELECTROCARDIOGRAM, PULSE RATE, OR BLOOD PRESSURE, NOR ON METABOLIC MARKERS IN THE LIVER, HEART, PANCREAS, OR KIDNEY. INTRAVENOUS NMN ADMINISTRATION APPEARS TO BE SAFE AND BENEFICIAL. IN ADDITION, THE FOLLOWING EFFICACY RESULTS WERE CONFIRMED.

INCREASES LONG-LIVED MOLECULE NAD+ LEVELS IN BLOOD BY ABOUT 20% (SEE NAD+ LEVEL GRAPH)

Improved sleep quality

BLOOD FAT LEVELS (TG LEVELS) REDUCED BY APPROXIMATELY 75% (SEE TG LEVEL GRAPH)

IMPROVEMENT OF TG LEVELS MAY LEAD TO PREVENTION AND TREATMENT OF FATTY LIVER AND DIABETES-RELATED DISEASES

TG LEVEL GRAPH

NAD+ LEVEL GRAPH

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