In May 2025, Abe Yoando Pharmaceutical was selected as one of the 40 teams to advance to the semi-finals of the"XPRIZE Healthspan," a global competition in which approximately 600 teams from around the world entered to develop technologies to rejuvenate people by 10 years.

Founded in 1731. The first generation of the company's founderAbe Yo-an Teiwa era, Jouan era (of the Northern Court) (1345.10.21-1350.2.27)(Camellia japonica 'Abeyoseada tasselana' (cultivar of common camellia)) The,
Its history began when it was called upon as the official physician of the Tokugawa and Matsudaira families,
Our philosophy and thoughts on health have spun out into the modern age after more than 290 years.
We should not get caught up in the mere elapsed years of "age."
It is said to keep the body's physical age young,
To realize the dreams that everyone has been envisioning,
YOANDO'S NMN EVOKES THE ORIGINAL DYNAMISM.

The 1st NMN

NMN (nicotinamide mononucleotide).
We have been conducting research on the safety and effects of NMN in humans since the days when it had not yet been decided whether NMN was a food or a drug.
We submitted the data obtained from our research to the Ministry of Health, Labour and Welfare and lobbied for a revision of the law to make NMN a food, which resulted in its approval as a food in 2020, a world first. The first product thus created is our NMN supplement.
In order to fulfill our responsibility as a pioneer, we will continue to produce NMN products that only we can make.

Rejuvenation through personal experience

TOMOTAKA ABE, THE 10TH GENERATION WHO WAS THE FIRST TO SELL NMN SUPPLEMENTS IN JAPAN, STARTED TAKING NMN EARLIER THAN ANYONE ELSE, AND DNA INFORMATION ANALYSIS CONDUCTED IN DECEMBER 2024 REVEALED THAT HIS BIOLOGICAL AGE IS MINUS 5.6 YEARS OLDER THAN HIS ACTUAL AGE. THE SPEED OF AGING IS ONLY 0.93 YEARS PER YEAR, AND UNLIKE REAL AGE, WHICH IS A NUMBER EQUALLY GIVEN TO EVERYONE, IT IS KNOWN TO BE SOMETHING THAT CAN BE CONTROLLED THROUGH LIFESTYLE AND TREATMENT.

  • Commitment to Development and Research

    THE FIRST GENERATION, DATING BACK NEARLY 300 YEARS, SUPPORTED HEALTH USING CHINESE MEDICINE, WHICH WAS CONSIDERED THE MOST ADVANCED AT THE TIME. THE ABE FAMILY HAS CONTINUED TO STUDY THE IDEAS AND TECHNIQUES OF ORIENTAL MEDICINE FOR GENERATIONS, AND TODAY, AS THE 10TH GENERATION, WE ARE FOCUSING ON THE USEFULNESS OF EVEN MORE ADVANCED INGREDIENTS TO CREATE PRODUCT DESIGNS THAT ONLY ABE YOANDO PHARMACEUTICAL CAN ACHIEVE THROUGH A FUSION OF TRADITION AND INNOVATION. IN RESEARCH, WE HAVE NOT ONLY CONDUCTED 10 YEARS OF RESEARCH ON THE DEVELOPMENT OF REJUVENATION TREATMENT TECHNOLOGY AT XPRIZE, BUT HAVE ALSO CONDUCTED RESEARCH WITH NUMEROUS UNIVERSITY TEAMS. OUR DEVELOPMENT CAPABILITIES WITH AN EMPHASIS ON EVIDENCE HAVE GIVEN BIRTH TO PRODUCTS THAT ARE THE RESULT OF OUR COMMITMENT TO EXCELLENCE.
  • Joint research/providing raw materials

    N-Pro®" and "N-Pro Med®", for which Abe Yohando Pharmaceutical holds the registered trademark, are provided as NMN research reagents to many universities researching the benefits of NMN. We also boast an approximately 80% share of the raw material supply to medical institutions. We believe that cooperation and understanding with various institutions pursuing the potential of NMN will support the future of Japan, a country of world-class longevity.

    The University of Tokyo School of Medicine
    Keio University
    Tokyo University of Science Graduate School of Medicine
    Graduate School of Decision Science and Technology, The University of Tokushima
    Hyogo Medical University School of Medicine
    Faculty of Food and Nutritional Sciences, University of Shizuoka
    Department of Veterinary Medicine, Faculty of Agriculture, Tottori University

Pioneering
responsibility and innovation.

AS A PIONEER IN THE FIELD OF NMN SUPPLEMENTS, ABE YO-ANDO-YAKUHIN WILL CONTINUE TO PURSUE SAFETY AND QUALITY IN RESEARCH AND DEVELOPMENT. WE WILL CONTINUE TO PROVIDE PRODUCTS OF HIGH SOCIAL VALUE, BELIEVING THAT THE FURTHER EXTENSION OF HEALTHY LIFE EXPECTANCY IS THE RESPONSIBILITY OF A COUNTRY WITH A LONG LIFE EXPECTANCY RECOGNIZED AROUND THE WORLD.

COMPANY

THE ABE FAMILY, THE FOUNDING FAMILY OF ABE YOAN-DO YAKUHIN, HAS BEEN CONTRIBUTING TO THE IMPROVEMENT OF THE LIVES AND WELFARE OF THE LOCAL COMMUNITY FOR MORE THAN 290 YEARS SINCE THE FOUNDING OF THE COMPANY BY THE FIRST GENERATION OF ABE YOAN SADAIMEI, A PHYSICIAN. THE DNA OF YOAN, WHICH HAS BEEN PASSED DOWN FROM GENERATION TO GENERATION, STILL EXISTS IN OUR COMPANY AND IS UTILIZED IN OUR DAILY PRODUCT DEVELOPMENT.
As a venture company in business for more than 290 years, we not only develop and sell supplements and skincare products in the field of "healthcare and aging care" but also actively conduct research for a society where people can stay young and healthy. We are actively engaged in research for a society where people can stay young. While constantly incorporating the latest science and evidence of the times, we will strive to provide value to a healthy society by utilizing the knowledge of our predecessors that has been cultivated over the years.

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